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A 23-year-old transgender woman is seen in a sexual health clinic and is diagnosed with rectal chlamydia. She undergoes HIV testing with an HIV-1/2 antigen-antibody immunoassay, and the result is positive. As part of your laboratory’s algorithm, an HIV-1/HIV-2 antibody differentiation assay is performed next.

Which one of the following is TRUE regarding the Geenius HIV 1/2 Supplemental Assay?

The Geenius HIV 1/2 Supplemental Assay is a single-use immunochromatographic test that utilizes multiple recombinant or synthetic peptides to detect HIV-1 antibodies (p31, gp160, p24, and gp41) and HIV-2 antibodies (gp36 and gp140). The test cassette as shown here contains seven test lines, including the six HIV peptides and one control.
Figure 1. Geenius HIV-1/2 Supplemental Assay
The Geenius HIV 1/2 Supplemental Assay is a single-use immunochromatographic test that utilizes multiple recombinant or synthetic peptides to detect HIV-1 antibodies (p31, gp160, p24, and gp41) and HIV-2 antibodies (gp36 and gp140). The test cassette as shown here contains seven test lines, including the six HIV peptides and one control.
Source: modified from Fernández McPhee C, Álvarez P, Prieto L, et al. HIV-1 infection using dried blood spots can be confirmed by Bio-Rad Geenius™ HIV 1/2 confirmatory assay. J Clin Virol. 2015;63:66-9.
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Question Last Updated
July 8th, 2024

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