Self-StudyCo-Occurring Conditions

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Lesson 1. Latent Tuberculosis Infection

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Latent Tuberculosis Infection Overview

About this Lesson

Last Updated: February 3rd, 2025

CNE/CME Continuing Education

This lesson qualifies for:

1 CME AMA PRA Category 1 Credit™, or
1 CNE contact hour and 1 CE contact hour (does NOT qualify for pharmacology CE for advanced practice nurses)

CNE and CME Origination: October 1st, 2017

CNE and CME Review: September 1st, 2023

CNE and CME Expiration: August 31st, 2026 (3rd Edition)

Steps to Acquire CE for this Lesson:

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Quiz

Score 80%+

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3rd Edition

This is a substantial revision of the original Lesson. The previous edition was titled Latent Tuberculosis Infection and available until September 1st, 2023.

Learning Objectives

Discuss the epidemiology of tuberculosis and HIV coinfection in the United States
State the rationale for screening for latent TB in people with HIV
Describe and compare recommended screening tests for latent TB in people with HIV
List recommended options for the treatment of latent TB in people with HIV
Summarize common drug interactions between medications used to treat latent TB and common antiretroviral medications

Lesson Contributors

Authors

Sylvia M. LaCourse, MD, MPH

Sylvia M. LaCourse, MD, MPH
Assistant Professor, Medicine, Global Health, and Epidemiology (Adjunct)
Division of Allergy & Infectious Diseases
University of Washington

Disclosures:

Grant to Institution: Merck

The relevant financial relationship was mitigated.

Aley G. Kalapila, MD, PhD

Aley G. Kalapila, MD, PhD
Associate Professor of Medicine
Division of Infectious Diseases
Emory University School of Medicine
Grady Health System

Disclosures:

None

Reviewers

David H. Spach, MD

David H. Spach, MD
Professor of Medicine
Division of Allergy & Infectious Diseases
University of Washington

Disclosures:

None

Lesson Plan

1Topic 1 Background

2Topic 2 Rationale and Indications for LTBI Screening

3Topic 3 Methods Used to Test for Latent Tuberculosis

4Topic 4 Recommended LTBI Testing in Persons with HIV

5Topic 5 Evaluation of Persons with a Positive LTBI Screening Test

6Topic 6 Management of LTBI in Persons with HIV

7Topic 7 Considerations in Special Populations

8Topic 8 Summary Points

Lesson Quiz Latent Tuberculosis Infection Quiz

Survey Lesson Survey

The National HIV Curriculum is supported by the Health Resources and Services Administration (HRSA) of the U.S. Department of Health and Human Services (HHS) as part of a financial assistance award totaling $1,172,990 with 0% financed with non-governmental sources. The contents are those of the author(s) and do not necessarily represent the official views of, nor an endorsement, by HRSA, HHS, or the U.S. Government. For more information, please visit HRSA.gov. This project is led by the University of Washington Infectious Diseases Education and Assessment (IDEA) Program.

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