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Lesson 6. HIV-2 Infection

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HIV-2 Infection Overview

About this Lesson

Last Updated: February 3rd, 2025

CNE/CME Continuing Education

This lesson qualifies for:
  • 1 CME AMA PRA Category 1 Credit™, or
  • 1 CNE contact hour and 1 CE contact hour (qualifies for pharmacology CE for advanced practice nurses)

CNE and CME Origination: September 17th, 2018
CNE and CME Review: September 1st, 2023
CNE and CME Expiration: August 31st, 2026 (3rd Edition)

View CE Notices

Steps to Acquire CE for this Lesson:

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Score 80%+
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3rd Edition

This is a substantial revision of the original Lesson. The previous edition was titled HIV-2 Infection and available until September 1st, 2023.

Learning Objectives

  • Contrast HIV-2 and HIV-1 epidemiology, natural history, and pathogenesis
  • Describe diagnostic testing for HIV-2
  • Summarize susceptibility of HIV-2 to antiretroviral medications
  • Discuss antiretroviral treatment recommendations for persons with HIV-2
  • Explain challenges with monitoring after starting antiretroviral therapy for HIV-2

Lesson Contributors

Authors

David H. Spach, MD
David H. Spach, MD
Professor of Medicine
Division of Allergy & Infectious Diseases
University of Washington
Disclosures:
None
Jehan Z. Budak, MD
Jehan Z. Budak, MD
Assistant Professor of Medicine
Division of Allergy & Infectious Diseases
University of Washington
Disclosures:
None

Reviewers

Geoffrey S. Gottlieb, MD, PhD
Geoffrey S. Gottlieb, MD, PhD
Professor of Medicine
Division of Allergy & Infectious Diseases
Adjunct Professor of Global Health
Medical Director, Environmental Health & Safety Department
Center for Emerging & Re-Emerging Infectious Diseases
University of Washington
Disclosures:
Grants to Institution: Abbot Molecular Diagnostics, Alere Technologies, Bristol-Myers Squibb, Ceres Corporation, Gilead Sciences, Janssen Pharmaceuticals, Merck & Co. Inc, Roche Molecular Systems, THERA Technologies/TaiMed Biologics, Inc., and ViiV Healthcare.
The relevant financial relationship was mitigated.

Lesson Plan

1Topic 1 Background

2Topic 2 HIV-2 Epidemiology

3Topic 3 Pathogenesis, Transmission, and Natural History of HIV-2

4Topic 4 2014 Surveillance Case Definition for HIV-2 Infection

5Topic 5 Diagnostic Testing for HIV-2

6Topic 6 Antiretroviral Susceptibility and Resistance

7Topic 7 HIV-2 Treatment Studies

8Topic 8 HIV-2 Treatment Recommendations

9Topic 9 Summary Points

Lesson Quiz HIV-2 Infection Quiz

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Quick Reference View

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Question Bank

Interactive board-review style questions about Epidemiology of HIV.

CNE/CME CME+MOC credits and CNE contact hours available.

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