A 58-year-old cisgender woman with advanced HIV immunosuppression (CD4 count 45 cells/mm3) presents for evaluation of thick white plaques on her buccal mucosa and hard palate. She was recently diagnosed with oral candidiasis and has taken oral fluconazole (100 mg per day) for 2 weeks with no improvement. She has a history of recurrent oral candidiasis, for which she has taken fluconazole numerous times. She does not have odynophagia. You discuss treatment options with her, and she states she does not want intravenous therapy.
Which one of the following oral therapy options would likely be most effective for this woman?
Figure 1. Pseudomembranous Candidiasis
Photograph courtesy of Mark Nichols, DDS, Dental Director, South Central AETC
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Question Last Updated
September 30th, 2023
September 30th, 2023
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