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Antiretroviral Therapy.

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Drug Interactions with Antiretroviral MedicationsQuestion 9/10

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A 58-year-old cisgender man who was diagnosed with HIV 10 years ago is seen in a clinic for a routine appointment. He has taken efavirenz-tenofovir DF-emtricitabine for approximately 8 years, and he consistently has an undetectable HIV RNA level. He has a significant past history of opiate use disorder and takes methadone 60 mg once daily via a methadone program. During the past 3 months, he has developed some depression, and the plan at this visit is to switch the antiretroviral regimen to bictegravir-tenofovir alafenamide-emtricitabine.

Following the change in antiretroviral therapy, which one of the following would be expected regarding methadone levels during the subsequent several weeks?

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Question Last Updated
August 28th, 2024

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