A 56-year-old patient with HIV has been stable for the last 2 years on an antiretroviral regimen of darunavir-cobicistat-tenofovir alafenamide-emtricitabine. Despite changing to a healthier diet and increasing their exercise, lipid values remain elevated: total cholesterol 272 mg/dL, low-density lipoprotein (LDL) 187 mg/dL, high-density lipoprotein (HDL) 32 mg/dL, and triglycerides 236 mg/dL. They have a strong family history of cardiovascular disease, and their father had a myocardial infarction at 52 years of age. They do not want to change their antiretroviral regimen but agree to start lipid-lowering therapy.