A 29-year-old woman with HIV and a CD4 count of 128 cells/mm3 returns for a follow-up visit. She has a 4-year history of type 1 diabetes mellitus, and for the last 12 months, she has taken the same insulin regimen. She reports that morning blood glucose levels have consistently ranged from 190 to 250 mg/dL, and she denies having any hypoglycemic episodes. Five months ago, they were diagnosed with HIV and started taking dolutegravir plus tenofovir alafenamide-emtricitabine and dapsone for Pneumocystis carinii prophylaxis. Laboratory studies obtained 5 months ago showed glycosylated hemoglobin (HbA1c) 8.2%, serum creatinine 1.1 mg/dl, and hematocrit 38%. Laboratory studies obtained at the current visit show HbA1c 5.6%, serum creatinine 1.2 mg/dL, and hematocrit 33%.
Which one of the following is the most likely cause of the recent lowering of the HbA1c value?
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Question Last Updated
February 1st, 2025
February 1st, 2025
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