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Common TitleSALT
Official Title Efficacy of Simplification to Atazanavir/Ritonavir + Lamivudine as Maintenance Therapy in Patients With Viral Suppression. Randomized, Open-label 96 Weeks Non-inferiority Trial
Phase Phase IV
ClinicalTrials.gov NCT01307488
Treatments
Atazanavir
Atazanavir Reyataz

Atazanavir

Tradename:ReyatazOther Names:ATVClass:Protease Inhibitors (PI)
Categories Treatment-ExperiencedSwitch/SimplificationDual Therapy
Funding
IndustryBristol Myers-Squibb and Fundación SEIMC-GESIDA
References
  • Perez-Molina JA, Rubio R, Rivero A, et al. Dual treatment with atazanavir-ritonavir plus lamivudine versus triple treatment with atazanavir-ritonavir plus two nucleos(t)ides in virologically stable patients with HIV-1 (SALT): 48 week results from a randomised, open-label, non-inferiority trial. Lancet Infect Dis. 2015;15:775-84.
    [PubMed Abstract]
  • Perez-Molina JA, Rubio R, Rivero A, et al. Simplification to dual therapy (atazanavir/ritonavir + lamivudine) versus standard triple therapy [atazanavir/ritonavir + two nucleos(t)ides] in virologically stable patients on antiretroviral therapy: 96 week results from an open-label, non-inferiority, randomized clinical trial (SALT study). J Antimicrob Chemother. 2017;72:246-253.
    [PubMed Abstract]

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