Common TitleMWRI-01
Official Title Phase 1 Open Label Safety, Acceptability, Pharmacokinetic and ex Vivo Pharmacodynamic Study of TMC278 Long Acting (LA) Administered Intramuscularly to HIV-1 Seronegative Individuals
Phase Phase I
ClinicalTrials.gov NCT01656018
Treatments
Rilpivirine
Rilpivirine
Tradename:EdurantOther Names:RPVClass:Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTI)Categories PREP
Funding
IndustryJanssen Research & Development, LLC
Non-IndustryBill & Melinda Gates Foundation
References
- McGowan I, Dezzutti CS, Siegel A, et al. Long-acting rilpivirine as potential pre-exposure prophylaxis for HIV-1 prevention (the MWRI-01 study): an open-label, phase 1, compartmental, pharmacokinetic and pharmacodynamic assessment. Lancet HIV. 2016;3:e569-e578.